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Friday, June 23, 2006

Continuation to the case study. :)
So any supporters for South Korean in the FIFA soccer world cup?

Differential Diagnosis
Madam XXX is likely to have painful pheripheral neuropathy on all 4 limps and I would like to propose the following aetiologies
1) Toxic causes
In view of her recent intake of ciprofloxacin although this is not a common agent that causes peripheral neuropathy.
Possible poisoning by toxins like arsenic are such substances are sometimes found in high levels in traditional Chinese medication.
2) Inflammatory Causes
She recently had a gastrointestinal infection which could lead to a sequelae of inflammatory demyelinating disease, although this usually presents with more motors symptoms. An atypical presentation of Acute Inflammatory Demyelinating Polyradiculoneuropathy(AIDP) is possible
3) Autoimmune causes
Autoimmune causes are possible although she has not showed any other signs of an autoimmune disease. This is more important since she had a recent allergic reaction to ciprofloxacin.
Other etiologies to consider:
Diabetic amyotrophy
Although the course is usually more chronic.
Nutritional Causes
Vitman B12 and folate are possible causes although the course is also usually more chronic and chronic deficiency of are not common in Singapore.
AIDS related neuropathy
The history does not suggest this, however it is noted that true sexual history of the patient and her partners are not easy to elicit.

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